Searching for the fundamental mental processes that cut across diagnostic categories, driving confusion and distress

A new paper in Journal of Clinical Psychology is the just the latest to take a trans-diagnostic approach to mental health

By Alex Fradera

The number of psychiatric diagnoses keep on growing, with perhaps ten times as many categories now as there were 50 years ago. This may in part reflect our growing knowledge, which is welcome. But the sheer density of diagnoses makes it difficult for researchers or clinicians to see the wood for the trees, and it encourages them to settle into silos. It would be advantageous for clinical research and practice if we could introduce some elegance to our understanding. A recent movement in psychology and psychiatry is seeking to do exactly this. It follows evidence that, in the words of US psychologists Robert Kruger and Nicholas Eaton in their 2015 review, “many mental disorders are manifestations of relatively few core underlying dimensions.” In the latest foray from this movement, the Journal of Clinical Psychology has published a review outlining another potential core feature: the repetitive occurrence of negative thoughts.

The proliferation of psychiatric diagnoses was baked in from the beginning. Modern psychiatry sought to apply the burgeoning medical model to the mind, treating madness as illness. Physical illnesses are considered as discrete categories, even if they produce overlapping symptoms like a fever, because we can point to their distinct microbial origins. 

This has influenced how we approach mental health, meaning someone struggling could be diagnosed with a phobia and also with an eating disorder and maybe separately with depression (and anxiety, and another eating disorder, and another phobia, and OCD…ad infinitum). We bracket these issues out as if they each originate from their own unique strain of mind bacteria. But mental disorders are rooted in dysfunctional mental processes, of which there are only so many. If we put aside the disease model and look for these processes, maybe we can get to a more solid and elegant foundation. 

One example would be internalising-externalising. In internalising disorders such as depression, OCD, anxiety and bulimia, the individual tends to draw problems inwards to an inappropriate degree; issues are suppressed or privately managed using ineffective or unhealthy strategies. Meanwhile, externalising disorders like pyromania, kleptomania, and conditions like oppositional defiant disorder or conduct disorder, all involve manifesting problematic thoughts or emotions by projecting them onto the world. 

According Kruger and Eaton’s landmark review, these aren’t just convenient labels: they may actually be more informative than the specific diagnoses. For instance, suicide risk may be better predicted by internalising in all its forms than a specific diagnosis like depression. Similarly, externalising behaviour of any kind is a strong predictor of other forms of externalising, suggesting that it might sometimes be useful to think of the problem as externalising, which can manifest in different ways depending on contextual factors. 

Still, this division is too simple to explain everything about mental health. But in interaction with some other features, perhaps we can start to arrive at a complete model that cuts across diagnostic categories while also capturing the richness of psychiatric conditions. What other relevant factors are there? We recently covered work that suggested another potential trans-diagnostic structure: meta-cognition, the ability to judge your cognitive ability. People who were more anxious or depressed showed more accuracy, but less confidence, in how they judged their performance on a mental task, whereas those who tended towards compulsive behaviour (such as those with schizophrenia or OCD) showed overconfidence and did less well. In our piece we described how this pattern can account for patterns of behaviour found in the real world, such as pessimism and jumping to conclusions, respectively.

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Now in the most recent example, Deanna Kaplan and her team at the University of Arizona suggest another trans-diagnostic feature: “maladaptive repetitive thought”. This is found across many mental health disorders, typically accompanied by a sense that the thoughts are uncontrollable, a negative flavour, and a fixation on seeking rather than solving problems. Consider the ruminative thoughts that characterise depression, the worries that surge up in anxiety, and the obsessive thoughts that drive OCD. Kaplan’s team suggest that these different manifestations should be thought of as variations on a key theme, often differing simply in whether the thoughts are focused on the past, present or future. 

The researchers note that their model helped them to draw connections to other related phenomena such as the problematic grief phenomenon of yearning, which pulls you into the past towards a desire that cannot be satisfied. They also see parallels in somatic hypervigilance, the constant monitoring of bodily sensations for any cause for alarm. Again, the same features come up: negative valence, uncontrollability, and seeking of problems, in this case in the present moment.

It’s not news that unwelcome thoughts are a frequent feature of poor mental health. But as with the internalising and externalising dimensions, it’s possible that grouping mental health problems that share repetitive thought processes could offer fresh way of looking at the root causes of people’s difficulties. It could be that the core problems driving all psychological disorders are countable on our fingers – if so, and if we can identity these core processes, then it will be easier to understand how they develop, and to apply advances from one area of treatment to another, as well as to see when doing so would be ill-advised.

For example, consider how the three features of internalising/externalising, meta-cognitive judgment and repetitive thought processes could be used to organise our understanding of the recently proposed diagnostic category of maladaptive daydreaming, whereby people are compulsively drawn to their daydreams at the cost of their psychological health. This certainly seems to involve internalising, and could involve overconfident misjudgment of whether the daydreaming is beneficial. And what is a daydream if not an extended, imagistic form of thought (much like a yearning)?

I believe we may be on the verge of a real advance in psychiatry, akin to the turn from individual symptoms to mental syndromes we made one hundred years ago. By looking past surface issues and gripping the fundamental mental processes that drive confusion and distress, we might be better placed to remedy them.

Maladaptive repetitive thought as a transdiagnostic phenomenon and treatment target: An integrative review

Alex Fradera (@alexfradera) is Staff Writer at BPS Research Digest

8 thoughts on “Searching for the fundamental mental processes that cut across diagnostic categories, driving confusion and distress”

  1. yea i figured it out already

    It’s essentially fear of pain which ties into belonging within the group that provides safety. The conflict between intimacy and the potential pain of rejection drives it all. One side is introverted the other is extroverted. Easy Peasy.

    1. Wao I read your article, it is quite incredible, you explain it very well, from my own experience I can only relate. I’ll try to keep that in mind in my day to day life. Very profound implications, that people should be aware of. Please write more, and add maybe some colors and diagram.

  2. This is not a new idea – there is overwhelming evidence that rumination is a significant transdiagnostic process. The following references are earlier articles that present the same idea:

    Querstret, D., & Cropley, M. (2013). Assessing treatments used to reduce rumination and/or worry: A systematic review. Clinical Psychology Review, 33, 996-1009. doi:10.1016/j.cpr.2013.08.004

    Grierson, A. B., Hickie, I. B., Naismith, S. L., & Scott, J. (2016). The role of rumination in illness trajectories in youth: linking trans-diagnostic processes with clinical staging models. Psychological medicine, 46(12), 2467-2484.

    Watkins, E. (2015). Psychological treatment of depressive rumination. Current Opinion in Psychology, 4, 32-36.

    Lyubomirsky, S., Layous, K., Chancellor, J., & Nelson, S. K. (2015). Thinking about rumination: The scholarly contributions and intellectual legacy of Susan Nolen-Hoeksema. Annual review of clinical psychology, 11, 1-22.

    Kinderman P, Schwannauer M, Pontin E, Tai S: Psychological processes mediate the impact of familial risk, social circumstances, and life events on mental health. PLOS ONE 2013, 8:e76564.

  3. The flaw in this approach is the underlying assumption that many, if not all psychiatric conditions are a result of thinking or thought processes. There is no actual evidence to support this idea, especially when one points out that depressive thoughts, for instance, can be either a cause of OR a result of the depression.

    As evidence we can point to depression associated with physical illness, possibly the genesis of depressive mechanisms that see a person suffering lethargy and anhedonia such that they are confined to bed, a behaviour most likely to aid recovery. In this condition people also have depressive thoughts even though the cause of their condition is entirely physical. Emotional trauma, such as the death of a loved one, also results in depressive thought processes.

    It is highly likely that clinical versions of natural depression also have a variety of initial causes including physical, emotional and thinking processes as well as existential crises such as the realisation of impending old age and the inevitability of death all of which are likely to eventually feature if the depression persists for long enough. By analogy, depression can metastasize, that is, spread from its original focus and become generalised so that regardless of the original cause, unhelpful, negative and inappropriate thought processes will eventually appear.

    The article does identify the various kinds of thinking processes related to various psychological conditions, but the implicit assumption that thinking is the sole cause can not be sustained.

  4. Janovian primal theory and therapy is based on the fact the human brain has three different levels of functioning, the thoughts, feelings and sensations. Our braistem sensations drive the rest of the brain above it. Primal therapy understands that most mental illness is caused by childhood trauma (basically lack of love), and that the cure is to connect back to the pain and release it. The fact that mental disorders can be cured by an “emotional” release is a foreign concept to psychiatry and psychology under the current paradigm.

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