Category: biological

biological, guest blogger, Health, Mental health, Therapy May 13, 2019May 13, 2019

There Is Limited Evidence To Support The Widely Held Belief That Psychotherapy Changes The Body As Well As The Mind

Looking at the latest epidemiological data, it could be argued that we are in the midst of a pandemic of mental illness, of dimensions never before seen in human history. The WHO estimates that over 350 million people around the world are presently suffering from depression, which constitutes almost 5-6 per cent of the population. At its extreme, depression may lead to suicide, by which it is estimated that around 1 million people die every year. And the numbers continue growing. Faced with this rising tide of illness, it is impossible to overestimate the importance of hard facts and data indicating the paths researchers and clinicians may follow in search of ways to help. Sometimes, as suggested by a meta-analysis of 50 years of studies on indicators that help predict suicide attempts, we are entirely helpless. In other cases, like with the recent meta-analysis of the neural correlates of the changes brought about by psychotherapy in depressed brains, study results do bring us hope.

The results of the first systematic review and meta-analysis of biological markers evaluated in randomized trials of psychological treatments for depression in Neuroscience and Biobehavioral Reviews are another attempt at understanding methods of treating this terrifying illness. The authors – Ioana A. Cristea, Eirini Karyotaki, Steven D. Hollon, Pim Cuijpers and Claudio Gentili – quite rightly point out that understanding how psychological interventions impact or are impacted by biological variables has important implications. For many people, their depression co-occurs with a bodily illness, such as cancer, diabetes, heart disease, and immune system and neurological disorders, and at times is a consequence of that illness. Although we still know little about the reciprocal cause-and-effect mechanisms between psychic and somatic symptoms, some studies have suggested that psychological interventions not only change mood, but also normalise the functioning of the autonomic nervous system, with a therapeutic effect on physical conditions, such as heart disease. But is this really true?

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biological, Cognition, Decision making April 12, 2019April 12, 2019

Being Prompted To Think About Coffee Elevates Your Physiological Arousal And Focuses Your Mind, No Ingestion Required

By Christian Jarrett

So entrenched is the association in our culture between coffee and ideas of arousal, ambition and focus that merely thinking about, or being reminded of, the drink is enough to increase the body’s arousal levels, in turn provoking a more focused, literal cognitive style. That’s according to Eugene Chan at Monash University and Sam Maglio at the University of Toronto Scarborough who, reporting their findings in Consciousness and Cognition, write that “… people may be more aroused simply after walking by a coffee shop. Not only would they be more aroused, but at a more downstream level, their decision making might shift as well.”

The intriguing results come from four studies involving hundreds of online and lab-based participants, but given the replication problems in the general area of “social priming” (concerned with how abstract ideas and sensory experiences can influence thoughts and behaviour, and vice versa), some readers may find that merely hearing about this new research is enough to elevate their pulse and alter their mindset to a more sceptical mode.

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biological, Genetics March 26, 2019March 26, 2019

Testosterone Increases The Aggressiveness Of Some Men More Than Others, Depending On Their Personality And Genes

By Emma Young

Having more testosterone makes men more aggressive – right? It’s a popular lay belief that’s supported by animal studies, but there’s been very little relevant research in humans. Now a study, published in Psychological Science, reveals a more nuanced picture: some men are more affected by raised levels of testosterone than others.

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biological, Brain, Drugs, Magic February 22, 2019May 21, 2019

Massive Comparison Of Narrative Accounts Finds Ketamine Trips Are Remarkably Similar to Near Death Experiences (NDEs), Supporting The Neurochemical Model Of NDEs

Screenshot 2019-02-22 at 09.26.54.png — Similarity in the most frequently used words in accounts of near death experiences (NDE) and ketamine trips, via Martial et al, 2019

By Christian Jarrett

First-hand accounts of what it is like to come close to death often contain the same recurring themes, such as the sense of leaving the body, a review of one’s life, tunnelled vision and a magical sense of reality. Mystics, optimists and people of religious faith interpret this as evidence of an after life. Sceptically minded neuroscientists and psychologists think there may be a more terrestrial neurochemical explanation – that the profound and magical near death experience is caused by the natural release of brain chemicals at or near the end of life.

Supporting this, observers have noted the striking similarities between first-hand accounts of near-death experiences and the psychedelic experiences described by people who have taken mind-altering drugs.

“I had the feeling of floating, still tied to the remains of my heavy body, but floating nonetheless. I rocked and moved, at times as if on a liquid, undulating surface, at other times rising upwards, like a helium-filled flat container.” Excerpt from Amazing First-time Experience in the K-hole, published by Phaeton at the Erowid Experience vaults.

Perhaps, near death, the brain naturally releases the same psychoactive substances as used by drug takers, or substances that act on the same brain receptors as the drugs. It’s also notable that psychedelic drugs have been taken by the shamans of traditional far-flung cultures through history as a way to, as they see it, visit the after world or speak to the dead.

To date, however, much of the evidence comparing near death experiences and psychedelic trips has been anecdotal or it’s been based on questionnaire measures that arguably struggle to capture the complexity of these life-changing experiences. Pursuing this line of enquiry with a new approach, an international team of researchers led by Charlotte Martial at the University Hospital of Liège has conducted a deep lexical analysis, comparing 625 written narrative accounts of near death experiences with more than 15,000 written narrative accounts of experiences taking psychoactive drugs (sourced from the Erowid Experience vaults), including 165 different substances in 10 drug classes.

Continue reading “Massive Comparison Of Narrative Accounts Finds Ketamine Trips Are Remarkably Similar to Near Death Experiences (NDEs), Supporting The Neurochemical Model Of NDEs” →

biological, Mental health December 13, 2018December 13, 2018

The physiological stress response is larger in the morning than evening

The real-world implications are far from clear and the result needs to be replicated with larger samples

By Emma Young

When’s the best time of day to give someone bad news? First thing in the morning or early evening? Yes, if it’s in the morning, they have longer to work out what to do about it, but you might be better off plumping for the evening because according to a new study, published open-access in Neuropsychopharmacology, they’re likely to suffer less of a physiological stress response at this time.

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biological, Health, Mental health November 20, 2018

The mood-stabilising effect of taking the pill has “downstream benefits” for women’s relationships, claims new study

By Christian Jarrett

In western nations, the vast majority of sexually active women take the birth control pill at some point in their lives, usually to avoid becoming pregnant. Of increasing interest to some psychologists, the hormone-stabilising effects of the pill may have other important effects, including on the psyche and personal relationships, and these are the focus of a new study in Neurology, Psychiatry and Brain Research.

Some earlier studies found that women who take the pill report more emotional stability, in terms of experiencing fewer depressive symptoms, and fewer mental health problems more generally (of course this is not true of all women, in fact some women describe unwanted emotional effects from the pill). There also appear to be what Tenille Taggart at San Diego State University and her colleagues refer to as “downstream benefits” of taking the pill, including greater relationship stability and satisfaction.

However, before now, no study has measured these two outcomes (emotional stability and relationship satisfaction) simultaneously. Taggart’s team have done this and their results suggest that a key reason that women who take the pill (oral contraceptives; OCs) tend to enjoy more satisfying relationships is because they have more stable emotions.

“Our results support previous findings that OCs may confer positive psychological benefits, and that one of these, mood stability, may have diffuse effects on women’s broader wellbeing and functioning,” they write.

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biological, Emotion, guest blogger October 8, 2018November 6, 2018

A cartography of consciousness – researchers map where subjective feelings are located in the body

By guest blogger Mo Costandi

“How do you feel?” is a simple and commonly asked question that belies the complex nature of our conscious experiences. The feelings and emotions we experience daily consist of bodily sensations, often accompanied by some kind of thought process, yet we still know very little about exactly how these different aspects relate to one another, or about how such experiences are organised in the brain.

Now, reporting their results in PNAS, a team of researchers in Finland, led by neuroscientist Lauri Nummenmaa of the University of Turku, has produced detailed maps of what they call the “human feeling space”, showing how each of dozens of these subjective feelings is associated with a unique set of bodily sensations.

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biological, evolutionary psych, Sport September 28, 2018October 2, 2018

This is what happened to fathers’ hormone levels when they watched their kids play football

By Christian Jarrett

The effect of playing sport on men’s testosterone levels is well documented. Generally speaking, the winner enjoys a testosterone boost, while the loser experiences the opposite (though far less studied, competition unsurprisingly also affects women’s hormonal levels, though not in the same ways as men’s). The evolutionary-based explanation for the hormonal effects seen in men is that the winner’s testosterone rise acts to increase their aggression and the likelihood that they will seek out more contests, while the loser skulks off to lick their wounds. When it comes to vicarious effects of competition on men’s testosterone, however, the findings are more mixed. There’s some evidence that male sports fans show testosterone gains after seeing their teams win, but other studies have failed to replicate this finding.

A new, small study in Human Nature adds to this literature by examining the hormonal changes (testosterone and cortisol) in fathers watching their children play a football game – a situation in which you might particularly expect to see vicarious hormonal effects since it’s the men’s own kin who are involved.

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Alcohol, biological, Brain, Cognition, guest blogger, Sleep and dreaming August 21, 2018August 21, 2018

New findings explain why, if you’re sensitive to alcohol, you’re probably sensitive to sleep deprivation too

By guest blogger Julia Gottwald

The last time you and your class-mates or co-workers pulled an all-nighter before a deadline, you may have noticed: there are always those lucky individuals who seem to do just fine after a lack of sleep, while others feel drowsy and confused – almost like they had too much to drink.

New research conducted at the German Aerospace Center suggests this could be because alcohol intoxication and sleep deprivation are more similar than we once thought.

In their study published recently in PNAS, Eva-Maria Elmenhorst and David Elmenhorst and their colleagues show how both affect us via a shared mechanism. And what’s more, if you’re sensitive to one, you’re likely to cope poorly with the other as well.

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